It is not known whether tolterodine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. The safety and effectiveness of meperidine in pediatric patients has not been established. Literature reports indicate that meperidine has a slower elimination rate in neonates and young infants compared to older children and adults. Neonates and young infants may also be more susceptible to the effects, especially the respiratory depressant effects. If meperidine use is contemplated in neonates or young infants, any potential benefits of the drug need to be weighed against the relative risk of the patient. where to buy furosemide in hong kong
Some MEDICINES MAY INTERACT with Detrol LA extended-release capsules. Symptoms may include difficulty breathing; difficulty urinating; dilated pupils; dry mouth; excitation; fast heartbeat; hallucinations; seizures. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Both tolerance and physical dependence can develop during chronic opioid therapy. Tolerance is the need for increasing doses of opioids to maintain a defined effect such as analgesia in the absence of disease progression or other external factors. Tolerance may occur to both the desired and undesired effects of drugs, and may develop at different rates for different effects.
Do not start, stop, or change the dosage of any medicines without your doctor's approval. Do not stop taking this medication without consulting your doctor. There is a relationship between increasing meperidine plasma concentration and increasing frequency of dose-related opioid adverse reactions such as nausea, vomiting, CNS effects, and respiratory depression.
Americans, most of them women. There are several different types, causes, and treatments. The findings cannot be clearly attributed to maternal toxicity. UpToDate: "Nutrition and Dietary Interventions in Adults with Inflammatory Bowel Disease. DEMEROL meperidine hydrochloride, USP Injection is an opioid agonist, available for intramuscular, intravenous, or subcutaneous administration.
The meperidine in Demerol Injection may increase the frequency of seizures in patients with seizure disorders, and may increase the risk of seizures occurring in other clinical settings associated with seizures. Monitor patients with a history of seizure disorders for worsened seizure control during Demerol Injection therapy. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Ask your pharmacist about the safe use of those products. This medication may make you sweat less, making you more likely to get heat stroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. If you overheat, quickly look for a place to cool down and rest. What should I discuss with my healthcare provider before taking tolterodine Detrol? Meperidine causes a reduction in motility associated with an increase in smooth muscle tone in the antrum of the stomach duodenum. Digestion of food in the small intestine is delayed and propulsive contractions are decreased. Propulsive peristaltic waves in the colon are decreased, while tone may be increased to the point of spasm, resulting in constipation. Other opioid-induced effects may include a reduction in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase. The half-life of meperidine is 2 to 5 hours, and the half-life of normeperidine is 15 to 30 hours. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your or local waste disposal company. Your condition will not improve any faster, and your risk of side effects will increase. Even if you have a kidney stone, you may not have any symptoms -- that is, until the stone goes on the move. It is readily soluble in water and has a neutral reaction and a slightly bitter taste. The solution is not decomposed by a short period of boiling. Consult your pharmacist for further advice. While many dieters swear by high-, eating large amounts of can also cause a stone to form.
Drug addiction is a cluster of behavioral, cognitive, and physiological phenomena that develop after repeated substance use and includes a strong desire to take the drug, difficulties in controlling its use, persisting in its use despite harmful consequences, a higher priority given to drug use than to other activities and obligations, increased tolerance, and sometimes a physical withdrawal. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. Inadvertent injection about a nerve trunk may result in sensory-motor paralysis which is usually, though not always, transitory. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Respiratory depression is the chief risk for elderly patients treated with opioids, and has occurred after large initial doses were administered to patients who were not opioid-tolerant or when opioids were co-administered with other agents that depress respiration. MAO inhibitors those intended to treat psychiatric disorders and also others, such as linezolid and intravenous methylene blue. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding. Studies in animals to evaluate the mutagenic potential of meperidine have not been conducted. What is the most important information I should know about tolterodine Detrol LA? The following adverse reactions associated with the use of meperidine were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Abuse of Demerol Injection poses a risk of overdose and death. The risk is increased with concurrent abuse of Demerol Injection with alcohol and other central nervous system depressants. lisinopril
This may interfere with certain laboratory tests such as possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug. What is tolterodine Detrol? How should I take tolterodine Detrol? Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs. If Demerol Injection is abruptly discontinued in a physically-dependent patient, a withdrawal syndrome may occur. Some or all of the following can characterize this syndrome: restlessness, lacrimation, rhinorrhea, yawning, perspiration, chills, myalgia, and mydriasis. Other signs and symptoms also may develop, including: irritability, anxiety, backache, joint pain, weakness, abdominal cramps, insomnia, nausea, anorexia, vomiting, diarrhea, or increased blood pressure, respiratory rate, or heart rate. The minimum effective analgesic concentration will vary widely among patients, especially among patients who have been previously treated with potent agonist opioids. If you get a kidney stone, you are in danger of getting more later in life. Let your doctor know right away if you notice an irregular heartbeat or have any dizziness or fainting episodes. Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Butorphanol, nalbuphine, pentazocine, buprenorphine. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using tolterodine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems heart failure, slow heartbeat, QT prolongation in the EKG family history of certain heart problems QT prolongation in the EKG, sudden cardiac death. when prandin uk prandin
Using corticosteroid for a long time can make it more difficult for your body to respond to physical stress. This product may increase your potassium levels. Before using potassium or salt substitutes that contain potassium, consult your doctor or pharmacist. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness; chest pain; confusion, disorientation, or memory problems; difficult or painful urination; fast or irregular heartbeat; fainting; hallucinations; severe dizziness; swelling of the hands, ankles, or feet. First, she will get a medical history and examine you. Physical dependence results in withdrawal symptoms after abrupt discontinuation or a significant dosage reduction of a drug. Tell your doctor if your condition does not improve or if it worsens such as your remain high or increase. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Carbon dioxide CO 2 retention from opioid-induced respiratory depression can exacerbate the sedating effects of opioids. Meperidine causes miosis, even in total darkness. To relieve dry mouth, suck sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute. Injections and surgery. Shots to bulk up your urethral area may help. In more extreme cases, you may need surgery. One procedure pulls the bladder back up to a more normal position, relieving the pressure and leakage. Caution is advised when using Detrol LA extended-release capsules in CHILDREN; they may be more sensitive to its effects, especially an increased risk for urinary tract infection and behavior or attention problems. Demerol Injection contains meperidine, a substance with a high potential for abuse similar to other opioids including fentanyl, hydrocodone, hydromorphone, methadone, morphine, oxycodone, oxymorphone, and tapentadol. Opioids cross the placenta and may produce respiratory depression and psycho-physiologic effects in neonates. An opioid antagonist, such as naloxone, must be available for reversal of opioid-induced respiratory depression in the neonate. Demerol Injection is not recommended for use in pregnant women during or immediately prior to labor, when other analgesic techniques are more appropriate. Opioid analgesics, including Demerol Injection, can prolong labor through actions which temporarily reduce the strength, duration, and frequency of uterine contractions. However, this effect is not consistent and may be offset by an increased rate of cervical dilation, which tends to shorten labor. Monitor neonates exposed to opioid analgesics during labor for signs of excess sedation and respiratory depression. etodolac purchase now online uk
If necessary, meperidine may be given intravenously, but the injection should be given very slowly, preferably in the form of a diluted solution. Rapid intravenous injection of narcotic analgesics, including meperidine, increases the incidence of adverse reactions; severe respiratory depression, apnea, hypotension, peripheral circulatory collapse, and cardiac arrest have occurred. Meperidine should not be administered intravenously unless a narcotic antagonist and the facilities for assisted or controlled respiration are immediately available. When meperidine is given parenterally, especially intravenously, the patient should be lying down. Opioids may also obscure the clinical course in a patient with a head injury. Avoid the use of Demerol Injection in patients with impaired consciousness or coma. Adults: The usual dosage is 50 mg to 150 mg intramuscularly or subcutaneously every 3 or 4 hours as needed for pain. Elderly patients should usually be given meperidine at the lower end of the dose range and observed closely. Mental or physical problems such as or prevent you from getting to the bathroom in time. Your doctor may occasionally change your dose to make sure you get the best results. Meperidine appears in the milk of nursing mothers receiving the drug. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Demerol Injection and any potential adverse effects on the breastfed infant from Demerol Injection or from the underlying maternal condition. Take this by with or without food as directed by your doctor, usually once or twice daily. Meperidine should therefore be used with caution in patients with renal impairment. Titrate the dosage of Demerol Injection slowly in patients with renal impairment and monitor closely for signs of central nervous system and respiratory depression. UpToDate: "Management of Mild to Moderate Ulcerative Colitis, "Nutrition and dietary interventions in adults with inflammatory bowel disease. Do NOT change your dose of Detrol LA extended-release capsules without checking with your doctor. In patients with pheochromocytoma, meperidine has been reported to provoke hypertension. The potential for these risks should not, however, prevent the proper management of pain in any given patient. Patients at increased risk may be prescribed opioids such as Demerol Injection, but use in such patients necessitates intensive counseling about the risks and proper use of Demerol Injection along with intensive monitoring for signs of addiction, abuse, and misuse. price lasix 100mg lasix
RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. Prolonged use of opioid analgesics during pregnancy may cause neonatal opioid withdrawal syndrome. Available data with Demerol Injection are insufficient to inform a drug-associated risk for major birth defects and miscarriage. Formal animal reproduction studies have not been conducted with meperidine. WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider. Talk to your doctor about using tolterodine safely. The meperidine in Demerol Injection may cause spasm of the sphincter of Oddi. Opioids may cause increases in serum amylase. Monitor patients with biliary tract disease, including acute pancreatitis, for worsening symptoms. Pfizer also has programs that provide eligible patients with insurance, support assistance, and medicines at a savings. Contact Pfizer RxPathways for details 844-989-7284. What are the possible side effects of tolterodine Detrol? Parenteral drug abuse is commonly associated with transmission of infectious diseases such as hepatitis and HIV. If a CYP3A4 or CYP2B6 inhibitor is discontinued, consider increasing the Demerol Injection dosage until stable drug effects are achieved. What happens if I miss a dose Detrol?
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. Meperidine produces peripheral vasodilation which may result in orthostatic hypotension or syncope. Although may be used to prevent problems or treat people who have problems, it may also rarely cause serious kidney problems or make them worse. Your doctor will check your kidney function while you are taking candesartan. Tell your doctor right away if you have any signs of kidney problems such as a change in the amount of urine. Contact local state professional licensing board or state controlled substances authority for information on how to prevent and detect abuse or diversion of this product. Blunt cannulas should not be recapped, purposely bent or broken by hand. This means you may dribble urine. This medicine may cause bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. Observational studies have demonstrated that concomitant use of opioid analgesics and benzodiazepines increases the risk of drug-related mortality compared to use of opioid analgesics alone. Use Detrol LA extended-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions. For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products. Adults: The usual dosage is 50 mg to 100 mg intramuscularly or subcutaneously, 30 to 90 minutes before the beginning of anesthesia. Elderly patients should usually be given meperidine at the lower end of the dose range and observed closely. It may be taken with or without food. The dosage is based on your medical condition and response to therapy. Surgery: Another way doctors can get rid of a kidney stone is to cut a small hole in your back and through your kidney in order to remove the stone. If this procedure is done, you could have to stay in the hospital for several days. Demerol Injection is contraindicated in patients with known or suspected gastrointestinal obstruction, including paralytic ileus. Assess each patient's risk for opioid addiction, abuse, or misuse prior to prescribing Demerol Injection, and monitor all patients receiving Demerol Injection for the development of these behaviors and conditions. Demerol Injection exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. phene.info microzide
If the decision is made to prescribe a benzodiazepine or other CNS depressant concomitantly with an opioid analgesic, prescribe the lowest effective dosages and minimum durations of concomitant use. In patients already receiving an opioid analgesic, prescribe a lower initial dose of the benzodiazepine or other CNS depressant than indicated in the absence of an opioid, and titrate based on clinical response. If an opioid analgesic is initiated in a patient already taking a benzodiazepine or other CNS depressant, prescribe a lower initial dose of the opioid analgesic, and titrate based on clinical response. Follow patients closely for signs and symptoms of respiratory depression and sedation. Limit dosage and duration to the minimum required. What happens if I overdose Detrol? What happens if I overdose Detrol LA? What Are Warnings and Precautions for Tolterodine? Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. What other drugs will affect tolterodine Detrol LA? This is also called . With this type, you have an urgent need to go to the bathroom and may not get there in time. Prolonged use of opioid analgesics during pregnancy for medical or nonmedical purposes can result in physical dependence in the neonate and neonatal opioid withdrawal syndrome shortly after birth. buy clonidine in cvs
Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Tolterodine is used to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence. Take Detrol LA extended-release capsules by mouth with or without food. Do 3 or 4 sets daily. If you have any questions about Detrol LA extended-release capsules, please talk with your doctor, pharmacist, or other health care provider. The stones can be brown or yellow, and smooth or rough. Do not use Demerol Injection in patients taking MAOIs or within 14 days of stopping such treatment. Intravenous hydrocortisone or prednisolone have been used to treat severe reactions, with the addition of intravenous chlorpromazine in those cases exhibiting hypertension and hyperpyrexia. The usefulness and safety of narcotic antagonists in the treatment of these reactions is unknown. buy eldepryl md aligne
Advise both patients and caregivers about the risks of respiratory depression and sedation when Demerol Injection is used with benzodiazepines or other CNS depressants including alcohol and illicit drugs. Advise patients not to drive or operate heavy machinery until the effects of concomitant use of the benzodiazepine or other CNS depressant have been determined. The most frequently observed adverse reactions include lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. These effects seem to be more prominent in ambulatory patients and in those who are not experiencing severe pain. In such individuals, lower doses are advisable. Some adverse reactions in ambulatory patients may be alleviated if the patient lies down. Drug-seeking" behavior is very common in persons with substance use disorders. Drug-seeking tactics include emergency calls or visits near the end of office hours, refusal to undergo appropriate examination, testing, or referral, repeated "loss" of prescriptions, tampering with prescriptions, and reluctance to provide prior medical records or contact information for other treating health care providers. "Doctor shopping" visiting multiple prescribers to obtain additional prescriptions is common among drug abusers and people suffering from untreated addiction. Preoccupation with achieving adequate pain relief can be appropriate behavior in a patient with poor pain control. This is a long-acting form of that is used to treat and urinary conditions. Medications, electrical stimulation, or surgery. Doctors sometimes prescribe medicines that block the of an overactive bladder. Electrical stimulation of the bladder nerves helps in some cases. Surgery is reserved for severe cases. It aims to increase the amount of urine your bladder can store. Methylprednisolone can make you more likely to get infections or may worsen any current infections. Therefore, well to prevent the spread of infection. Talk to your doctor or about lifestyle changes that might benefit you. Avoid becoming overheated in hot weather, saunas, and during or other strenuous activity. Store at room temperature away from light and moisture. not store in the bathroom. Keep all away from children and pets. The usual dosage is 50 mg to 100 mg intramuscularly or subcutaneously when pain becomes regular, and may be repeated at 1- to 3-hour intervals. armidex
Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required. QTdrugs List, AZCERT, Inc. Do not use Demerol Injection in patients taking MAOIs or within 14 days of stopping such treatment. If any of these effects persist or worsen, tell your doctor or promptly. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. These help to strengthen the pelvic floor after childbirth. They also help prevent stress incontinence. Best of all, you can do Kegels anytime, anywhere. Oxybutynin belongs to a class of drugs known as antispasmodics. Some medical conditions may interact with Detrol LA extended-release capsules. Detrol LA extended-release capsules should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. Monitor for signs of opioid withdrawal. With this type, urine leaks due to weakened pelvic floor muscles and tissues. Detrol LA extended-release capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people. The dose should be titrated to the needs of the patient and will depend on the premedication and type of anesthesia being employed, the characteristics of the particular patient, and the nature and duration of the operative procedure. Elderly patients should usually be given meperidine at the lower end of the dose range and observed closely. Dosage should be adjusted according to the severity of the pain and the response of the patient. While subcutaneous administration is suitable for occasional use, intramuscular administration is preferred when repeated doses are required. If intravenous administration is required, dosage should be decreased and the injection made very slowly, preferably utilizing a diluted solution. This may not be a complete list of all interactions that may occur. Ask your health care provider if Detrol LA extended-release capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
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Your doctor will pass the scope through your bladder and ureter into your kidney. She uses a small basket to remove small stones. If the stones are larger, the doctor will pass a laser through the scope to break them up. Typically, you are able to go home on the same day. When a patient who has been taking Demerol Injection regularly and may be physically dependent no longer requires therapy with Demerol Injection, taper the dose gradually, by 25% to 50% every 2 to 4 days, while monitoring carefully for signs and symptoms of withdrawal. If the patient develops these signs or symptoms, raise the dose to the previous level and taper more slowly, either by increasing the interval between decreases, decreasing the amount of change in dose, or both. promethazine
Although the risk of addiction in any individual is unknown, it can occur in patients appropriately prescribed Demerol Injection. Addiction can occur at recommended dosages and if the drug is misused or abused. Drink plenty of water: You should drink at least 64 ounces of water each day. Some of that liquid can be orange juice, lemonade, or limeade. Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. Chronic use of opioids may cause reduced fertility in females and males of reproductive potential. cheapest gynera order now online
What should I avoid while taking tolterodine Detrol LA? Tolterodine may also be used for purposes not listed in this medication guide. This drug may make you dizzy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit beverages.
Take this medication by mouth with or without food as directed by your doctor, usually once a day. Swallow the medication whole with a full glass of liquid. Do not crush or chew the medication. Doing so can destroy the long action of the drug and may increase side effects. Demerol Injection, like other opioids, can be diverted for non-medical use into illicit channels of distribution. Careful record-keeping of prescribing information, including quantity, frequency, and renewal requests, as required by state and federal law, is strongly advised. Demerol Injection is achieved. Similarly, discontinuation of a CYP3A4 inducer, such as rifampin, carbamazepine, and phenytoin, in DEMEROL-Injection treated patients may increase meperidine plasma concentrations and prolong opioid adverse reactions.